Restoring Tacrolimus-Induced Impaired Barrier Function
نویسندگان
چکیده
منابع مشابه
5-Aminosalicylic acid inhibits the impaired epithelial barrier function induced by gamma interferon.
Gamma interferon (IFN gamma) impairs epithelial barrier function and induces HLA-DR expression on colonic cancer cell lines. Salicylates have been shown to reduce IFN gamma induced HLA-DR expression. The effect of 5-aminosalicylic acid (5-ASA) on IFN gamma induced changes in transepithelial resistance and permeability was investigated in HT29 clone 19A and Caco 2 monolayers. Monolayers were inc...
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Atopic dermatitis (AD) is a chronic, inflammatory, pruritic skin disease with increasing prevalence. The etiopathogenesis of atopic dermatitis is multifactorial and involves a complex interplay of environmental and genetic factors that induce derangements in the structure and function of the epidermal barrier and immune system. Due to great heterogeneity of etiopathogenesis, there is also great...
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O ur skin is the natural barrier that protects us from the environment. Some of the most important functions of the skin are blocking external pathogens and other substances from penetrating the body and preventing water loss. These functions are performed primarily by the epidermis by producing a protective, highly impermeable layer (stratum corneum) that permits survival under Earth condition...
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ژورنال
عنوان ژورنال: Journal of Investigative Dermatology
سال: 2011
ISSN: 0022-202X
DOI: 10.1038/jid.2010.431